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KMID : 0858420090110020078
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Korean Journal of Stroke
2009 Volume.11 No. 2 p.78 ~ p.81
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Stroke Update 2009: Translational Stroke Research
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Kim Dong-Eog
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Abstract
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Translational research helps translate scientific discoveries from bench to clinic. In this brief review, the results of recent translational stroke research are summarized. It covers pathology of thrombi in acute stroke, heart and vessel pathology of autopsied stroke patients, aging-related white matter vulnerability to ischemia, Kindlin-3 on platelet aggregation, a role of matrix metalloproteinase in neuropathic pain, a mechanism of hyperglycemia-induced stroke aggravation via nicotinamide adenine dinucleotide phosphate oxidase, molecular imaging of stroke inflammation, and modulation of tissue plasminogen activator-induced blood brain barrier disruption using Imatinib, a platelet-derived growth factor-α inhibitor
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KEYWORD
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Translational research, Stroke, Review
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